Abstract
Chemical investigation of the root extract of Valeriana officinalis afforded a new bicyclic sesquiterpene acid, (-)-3β,4β-epoxyvalerenic acid together
with valerenic acid and hexadecanoic acid. The structure of the new compound was elucidated
by spectroscopic data and confirmed by partial synthesis of its methyl ester from
valerenic acid. Methyl (-)-3α,4α-epoxyvalerenate was obtained as a minor product from
the above reaction.
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N.P. Dhammika Nanayakkara
National Center for Natural Products Research
School of Pharmacy
The University of Mississippi
University, MS 38677
Fax: 662-915-7989
Email: dhammika@olemiss.edu
